Why I Believe Microneedling with Exosomes Is Better Than PRP

Expert skin science insights an award-winning holistic aesthetic clinic in Altrincham. Written by Dr Caroline Warden, NHS GP, cosmetic dermatology specialist

Skin regeneration treatments have evolved dramatically in recent years, offering patients increasingly effective, minimally invasive options for rejuvenation. Two of the most discussed treatments are PRP (Platelet-Rich Plasma) and microneedling with exosomes and while both stimulate natural healing and skin repair, there is a growing shift in the aesthetic industry toward exosome-based skin therapies.

As a doctor-led aesthetic clinic specialising in advanced regenerative skin treatments, I have seen first-hand how exosomes deliver faster, more predictable and more powerful results than PRP for many patients.

Here is why I believe microneedling with exosomes is a superior choice for skin rejuvenation.

What Is PRP?

PRP, sometimes known as the “vampire facial”, uses the patient’s own blood. The blood is spun in a centrifuge to separate plasma, which is then applied or injected back into the skin to stimulate repair and collagen production.

Benefits of PRP

  • Uses the patient’s own biological material

  • Natural stimulation of collagen and elastin

  • Can improve texture, pigmentation and fine lines

However, results can vary significantly from patient to patient.

What Are Exosomes?

Exosomes are highly advanced cellular messengers derived from stem cells. They act like communication signals that tell skin cells to repair, regenerate and produce collagen at a significantly enhanced rate.

When combined with microneedling which creates controlled micro-channels in the skin — exosomes penetrate deeply and trigger accelerated healing and skin transformation.

Benefits of Exosomes

  • Reduce inflammation and repair damaged tissue

  • Increase collagen and elastin production

  • Improve skin tone, texture and hydration

  • Enhance healing and reduce downtime after microneedling

  • Suitable for sensitive skin and rosacea

Microneedling with Exosomes vs PRP: Key Differences

Feature Microneedling + Exosomes PRP
Consistency of results Predictable, reliable Highly variable
Growth factor concentration Extremely high Dependent on patient health & blood quality
Downtime Minimal More swelling & inflammation
Comfort Gentle and soothing Requires blood draw & can feel intense
Suitability Works for most skin types including rosacea Not ideal for low platelet levels
Visible results Faster (2–4 weeks) Slower (6–12 weeks)
Scientific advancement Next-generation cellular therapy Older regenerative method

Why I Prefer Exosomes in My Doctor-led clinic in Hale

1. More Advanced Science

Exosomes contain billions of signalling molecules that instruct skin cells to regenerate more efficiently. They deliver a stronger biological message than PRP can.

2. More Predictable Results for All Patients

PRP effectiveness depends heavily on:

  • Age

  • Hormone levels

  • Lifestyle and nutrition

  • Platelet concentration

  • Hydration

  • Medications

Meaning two people having the same treatment can have drastically different results.

Exosomes deliver consistent performance every time, regardless of patient variability.

3. Superior Healing & Reduced Redness

Because exosomes are anti-inflammatory, patients experience:

  • Less redness post-treatment

  • Faster healing time

  • Less risk of flare-ups (especially beneficial for rosacea sufferers)

4. More Comfortable Treatment Experience

There is:

  • No blood draw

  • No bruising from injections

  • A more pleasant and spa-like experience compared to PRP

5. Stronger Anti-Ageing Performance

Exosomes significantly increase:

  • Collagen production

  • Cell turnover

  • Tissue regeneration

  • Hydration

Leading to visibly smoother, firmer, brighter skin.

Real Patient Case Study

Patient: Female, 47

Concerns: Rosacea-related redness, dullness, early fine lines, uneven texture

Previous Experience: Had PRP elsewhere, experienced significant swelling and no noticeable improvement after three sessions

Treatment Plan

  • Microneedling using Exosomes + LED healing

  • Three treatments spaced four weeks apart

  • Home skincare routine simplified to support skin barrier repair

Results

After the second treatment the patient noticed:

  • Brighter, healthier looking skin

  • Reduction in redness and inflammation

  • Smoother texture and softer lines under the eyes

  • Significantly improved confidence and comfort without makeup

Patient Feedback

“I feel like my skin has finally changed. I didn’t see results with PRP but exosomes have transformed my texture and redness — friends keep saying I’m glowing.”

Who Is Microneedling with Exosomes For?

Ideal for patients who want to:

  • Improve fine lines and wrinkles

  • Reduce pigmentation and sun damage

  • Strengthen skin barrier

  • Treat rosacea or sensitive skin

  • Minimise pores and acne scarring

  • Achieve general skin rejuvenation

Summary: Why Exosomes Are the Future of Regenerative Skin Treatments

In my professional opinion, microneedling with exosomes:



  • Offers faster, more predictable and more comfortable results than PRP

  • Works more effectively for a wider range of patients

  • Creates deeper cellular repair and regeneration

  • Gives visible benefits after fewer sessions



For those seeking the next-level skin transformation, exosomes are the most advanced option currently available.

Book a Consultation

If you are considering PRP or exosome microneedling and want honest guidance based on your skin goals:


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Book in for a Consultation at your local, doctor-led, sister-run skin & aesthetics sanctuary for natural, bespoke results

Dr Caroline Warden is an experienced NHS GP and aesthetic doctor. She has been a medical doctor for over 18 years. She runs the female-led family business with her sister Louise Devereux (creative director & patient co-ordinator)

Their main Skin and Aesthetic Clinic is located in Hale, Cheshire but they also run a pop-up clinic in Disley, Stockport one evening a week.

You will only ever see and have treatments with Dr Caroline Warden.

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Whether you're new to aesthetic treatments or ready to refine your routine, her bespoke skin assessments are the best place to start. Dr Caroline Warden will design a tailored plan based on your skin goals, lifestyle, and timeline.

Book your consultation at the clinic in Hale, Cheshire and experience aesthetic medicine.


You’ll be guided through your medical history, goals, and expectations so you can make an informed choice.

Where our clinics are local to:

Our flagship main Hale clinic is conveniently located for patients travelling from:

Alderley Edge, Altrincham, Bowdon, Bramhall, Hale Barns, Knutsford, Manchester, Mobberley, Sale, Timperley, Urmston, Wilmslow, Handforth, Poynton, Cheadle, Didsbury and Warrington.

Our satellite Disley clinic (Thursday evenings at Scott, Skin & Co) is ideal if you’re based in:

New Mills, High Lane, Marple, Mellor, Whaley Bridge, Strines, Chapel, Hayfield or Stockport.

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