Profhilo® & Skin Boosters
Doctor-Led treatments in Hale, Altrincham & Cheshire
Hydration, firmness and glow, from the inside
Skin boosters are injectable treatments that improve the quality of your skin rather than its shape. They deliver hyaluronic acid, and in some cases vitamins, amino acids and polynucleotides, into the skin itself, where they hold water, support collagen and restore the hydration, elasticity and radiance that time and hormones take away. At my clinic in Hale, near Altrincham, they are one of the most requested treatments, and Profhilo is the one I use most.
I am Dr Caroline Warden, an NHS GP with over nineteen years of clinical experience, an independent prescriber and a Level 7 qualified aesthetic doctor trained at Harley Academy, practising aesthetic medicine since 2017. Every skin booster consultation and treatment at the clinic is carried out by me personally, and the products I use, Profhilo, NCTF 135 HA, Redensity 1 and NEWEST, are all CE-marked, evidence-backed and made by established European pharmaceutical companies. The clinic was named Best Doctor-Led Aesthetic Clinic in Cheshire 2026 by GHP.
If what your skin needs is hydration and firmness rather than volume, this is the page. If it needs structure or lift, I will say so, and point you towards Sculptra or the facial volume loss guide instead.
Good to know
Profhilo is two sessions four weeks apart, then a top-up around every six months. Strong numbing cream, under ten minutes of injections. Small bumps at the injection points for a few hours. Glow within two weeks, firmness building over two to three months. Profhilo course £550; top-up £295; NCTF, Redensity 1 and NEWEST priced by area at consultation.
On this page:
- What are skin boosters and how do they work?
- Which skin boosters I use, and why
- Profhilo: why it is my first choice
- What can skin boosters treat?
- Skin boosters, polynucleotides or filler?
- What to expect at your appointment
- Results, course and how long they last
- Safety and suitability
- Prices
- Frequently asked questions
What are skin boosters and how do they work?
A skin booster is injected into the superficial layers of the skin, not beneath it. The hyaluronic acid it contains is non-crosslinked or lightly stabilised, so instead of holding a shape the way a filler does, it spreads, attracts water and hydrates the skin at a cellular level. Well-hydrated skin behaves differently: fibroblasts work better, collagen and elastin production is supported, and over the following weeks the skin becomes smoother, firmer and more luminous. The change is in how your skin looks and feels, never in the shape of your face.
The products differ in what they add to the hyaluronic acid and in how they are placed, which is why I keep four rather than one.
Which skin boosters I use, and why
Dr Caroline's note
I do not keep four products so that you can choose one. I keep them so that I can. For most faces Profhilo gives the best combination of hydration and firmness and the simplest course. I reach for NCTF when the skin looks exhausted rather than lax, Redensity 1 for very fine lines on delicate skin, and NEWEST when I want the regenerative effect of polynucleotides and the hydration of hyaluronic acid in a single treatment. You do not need to know which before you come.
Profhilo: why it is my first choice
Profhilo was the first injectable to describe itself as a bioremodeller rather than a filler, and the description holds. Its hybrid of high and low molecular weight hyaluronic acid, produced without chemical crosslinkers, spreads through the tissue after injection rather than sitting where it is placed. That is why it is given at just five points on each side of the face, the Bio Aesthetic Points, and why the result is an even improvement across the whole area rather than a change in any one spot.
What patients notice first, within two weeks, is glow: skin that looks hydrated and rested. What they notice by two to three months after the second session is firmness: the early laxity along the jaw and under the cheeks tightens, crepiness softens, and make-up sits differently. Published studies of the hybrid complex have reported improvements in hydration, elasticity and skin texture on the face and neck, and it is the skin booster with the longest track record in my own practice. It also works beautifully on the neck and the hands.
What can skin boosters treat?
Skin boosters, polynucleotides or filler?
They combine well. Polynucleotides with a skin booster is a pairing I use constantly, and Profhilo after a Sculptra course finishes the skin over the new structure. I wrote about the choices in Profhilo vs skin boosters: which is best for you? and why I combine polynucleotides with skin boosters.
Skin boosters change how your skin looks, never how your face is shaped. That is exactly why they are the first injectable I suggest to so many patients.
What to expect at your appointment
Good to know
For a week before, avoid fish oil, vitamin E, ginkgo, garlic supplements and ibuprofen to reduce bruising; do not stop prescribed aspirin or blood thinners without advice. Afterwards, expect small raised bumps at the Profhilo points for a few hours and possibly mild redness or a bruise. No make-up for a few hours, no vigorous exercise, saunas or alcohol for 24 to 48 hours. Most people go straight back to their day.
Results, course and how long they last
Profhilo is a course of two sessions four weeks apart, which is when most patients see their best result, followed by a single top-up around every six months. NCTF, Redensity 1 and NEWEST are given as a short course of sessions a few weeks apart, tailored to the skin, with the number and spacing confirmed at consultation.
Dr Caroline's note
The second Profhilo session is not optional. The first gives you hydration; the second is where the firmness comes from, because it is the repeated signal that gets fibroblasts working. Patients who have both, then a top-up at six months, keep a result that most people would take for simply having good skin.
Safety and suitability
Skin boosters use ultra-pure hyaluronic acid, manufactured to remove protein residues and other impurities, so reactions are rare and the safety record is long. They are still an injectable medical treatment and every patient has a consultation first.
Treatment is not suitable in pregnancy or breastfeeding, with an active skin infection or cold sore in the area, with a known allergy to hyaluronic acid or (for NEWEST) to fish, or with certain autoimmune or bleeding conditions. If you take blood-thinning medication, tell me and we plan around a higher chance of bruising rather than stopping anything.
Prices
Current prices are on the price list.
Frequently asked questions
What is the difference between Profhilo, NCTF, Redensity 1 and NEWEST?
All contain hyaluronic acid. Profhilo has the highest concentration and gives hydration plus firmness. NCTF and Redensity 1 add vitamins, amino acids and antioxidants to revitalise tired or delicate skin. NEWEST combines hyaluronic acid with polynucleotides for regeneration and hydration in one product. The table above sets them out.
Which skin booster is best?
For most faces, Profhilo. For exhausted-looking skin, NCTF. For fine lines on delicate skin, Redensity 1. For thinning plus dehydration, NEWEST. I decide at consultation.
How long do skin booster results last?
Profhilo six to nine months after a course; NCTF and Redensity 1 four to six months; a top-up keeps the result going.
What is the downtime?
Small bumps at the Profhilo points for a few hours; possible mild redness or bruising for a few days. Most patients go straight back to their day.
Are skin boosters painful?
Mildly uncomfortable at most. Strong numbing cream first, and the injections take under ten minutes.
Do skin boosters add volume?
No. They hydrate and firm the skin without changing its shape. If you need volume, filler or Sculptra is the better tool.
Can skin boosters be combined with other treatments?
Yes, and often. Polynucleotides for regeneration, Sculptra for structure, microneedling for texture, skincare underneath all of it. I sequence them at consultation.
Do skin boosters help under the eyes?
Yes. I use NCTF under the eyes, usually alongside polynucleotides, for dehydrated, dull or finely lined under-eye skin. See the under-eye guide.
Can I have Profhilo on my neck or hands?
Yes. Both respond well. The neck and décolletage are among the most rewarding areas for Profhilo.
What does "ultra-pure hyaluronic acid" mean?
Hyaluronic acid purified to remove protein residues and impurities from manufacturing, which reduces the risk of inflammation or allergy. All four products are made to this standard.
Who is suitable, and who should avoid them?
Most adults wanting better hydration, texture and glow. Not in pregnancy or breastfeeding, with an active infection or cold sore, or with a known allergy to hyaluronic acid. Autoimmune conditions and blood thinners are discussed individually.
At what age should you start?
There is no fixed age. Some patients start in their early thirties as prevention; for many it becomes relevant in the forties and fifties as hormones affect hydration and collagen. What matters is how your skin looks and feels.
Is Profhilo the same as a skin booster?
It is one type: a bioremodeller with a very high hyaluronic acid concentration and a distinct five-point technique. "Skin booster" covers the whole group.
Related reading
- Profhilo vs skin boosters: which treatment is best for you?
- Skin boosters in facial aesthetics: natural hydration, glow and skin quality
- Why I combine polynucleotides with skin boosters
- Why collagen declines and the treatments that actually stimulate it
- The best aesthetic treatments for menopausal skin
- Polynucleotides in Hale, Altrincham and Cheshire
- Neck and décolletage treatment
Next steps
Learn more about Dr Caroline Warden Clinic
Learn more about other treatments offered
Written and medically reviewed by Dr Caroline Warden, NHS GP with over 19 years of clinical experience, independent prescriber and Level 7 qualified aesthetic doctor (Harley Academy). GMC 6157708. Dr Caroline Warden Skin & Aesthetic Clinic, 2 Crown Passages, Hale, Altrincham, Cheshire WA15 9GN. Results vary between individuals; suitability is determined at a face-to-face consultation. Last reviewed: 2 October 2026.