Profhilo vs Other Skin Boosters: Which Treatment Is Best for You in Altrincham?
Expert skin science insights an award-winning holistic aesthetic clinic in Altrincham. Written by Dr Caroline Warden, NHS GP, cosmetic dermatology specialist and leading aesthetic doctor in Hale, South Manchester
Over the past few years, non-surgical skin rejuvenation has become the fastest-growing area in aesthetic medicine. Patients increasingly want better skin, not a different face smoother texture, improved hydration, healthier glow and natural, understated rejuvenation.
At my doctor-led aesthetic clinic in Hale, the two most requested treatments for this are:
✨ Profhilo
✨ Other Skin boosters (such as Redensity 1, Fillmed NCTF 135HA and polynucleotides)
But patients often ask:
“Which is better for me
“Do they do the same thing?”
“How do I choose?”
This comprehensive guide explains the differences, benefits, and ideal candidates for each treatment so you can make a confident decision about your skin.
What Is Profhilo?
Profhilo is one of the most advanced injectable skin treatments available and is considered the gold standard for improving skin quality.
It contains one of the highest concentrations of ultra-pure hyaluronic acid (HA) on the market but because it’s not crosslinked, it does not act like filler. Instead, it spreads evenly under the skin to trigger:
Collagen production
Elastin production
Hydration
Tissue remodelling
Skin tightening
Profhilo is particularly powerful for:
Crepey skin on the cheeks
Sagging or loss of firmness
Skin laxity around the jawline
Dull, dehydrated skin
Fine lines on the neck
Treatment plan:
Two sessions, four weeks apart, then maintenance every 6 months.
What Are Skin Boosters?
Skin boosters are very light injectable treatments designed to improve:
Hydration
Glow
Fine lines
Texture
Skin quality
Different boosters have different ingredients, benefits and ideal treatment areas. Here are the ones I use extensively in clinic besides Profhilo (the most well known)
1. Teosyal Redensity 1
A beautiful option for tired, dull, dehydrated or sun-damaged skin.
Redensity 1 contains:
Hyaluronic acid
8 amino acids
3 antioxidants
Minerals
Vitamin B6
It gives an instant glow and is particularly effective for:
Tech neck lines
Crepey cheeks
Early fine lines
Décolletage rejuvenation
Under-eye brightness
Best for: radiance, hydration, a “lit-from-within” glow
2. Fillmed NCTF 135HA
Fillmed NCTF 135HA is one of the most advanced mesotherapy-style skin boosters available. It contains over 50 active ingredients, including:
Hyaluronic acid
Amino acids
Coenzymes
Vitamins
Minerals
Nucleic acids
Antioxidants
This makes it exceptional for improving:
Dullness
Uneven texture
Fine lines
Skin density
Early ageing
Lack of vibrancy
Best for: full-face rejuvenation, pore refinement, long-term skin health
3. Polynucleotides
One of the biggest breakthroughs in regenerative aesthetics.
Polynucleotides help to:
Reduce inflammation
Increase elasticity
Repair damaged or fragile skin
Strengthen the extracellular matrix
Improve crepey under-eyes
Reduce redness (great for rosacea-prone skin)
Best for: regeneration, elasticity, thin or fragile skin, under-eye rejuvenation.
Why I Do NOT Use Seventy Hyal
Although Seventy Hyal is popular online, it’s not a product I choose to use in my medical clinic.
Here’s why:
1. Limited clinical evidence
Compared to Profhilo, Redensity 1 and Fillmed NCTF 135HA, Seventy Hyal lacks independent long-term studies.
2. High molecular weight HA alone
It does not include vitamins, minerals, amino acids or coenzymes — meaning it offers hydration but not the multi-layered skin health benefits of premium boosters.
3. Inconsistent results
Patients who have previously tried Seventy Hyal often report:
Short-lived results
Minimal textural improvement
Not enough glow
No reduction in fine lines
I prefer clinically robust, evidence-based products with proven outcomes.
Profhilo vs other Skin Boosters: What’s the Difference?
Profhilo
✔ Lifts and tightens
✔ Remodels skin
✔ Improves crepiness
✔ Deep hydration
✔ Improves elasticity
Best for: lower face, cheeks, neck, jawline
Other Skin Boosters
✔ Hydration
✔ Glow
✔ Fine-line smoothing
✔ Texture improvement
✔ Brightening
Best for: under-eyes, crepey cheeks, neck, chest
Can You Combine Profhilo & other Skin Boosters?
Absolutely, in fact, this is one of the most transformational skin protocols.
Example combination:
Profhilo: structure + firmness
Redensity 1 or NCTF: glow + hydration + texture
Polynucleotides: regeneration + strengthening
Together, they improve every layer of the skin.
Real Patient Case Study: “Sarah, 48 — Dullness, Fine Lines & Crepey Skin”
Concerns
A patient (we’ll call her Sarah) visited my Hale clinic feeling that her skin looked “tired, flat and crepey,” especially around her lower cheeks and neck. She also struggled with dehydration and early laxity but did not want filler or anything that would change her facial shape.
Assessment:
On examination, Sarah had:
Mild loss of elasticity
Fine lines on the neck
Dehydrated skin
Textural dullness
Crepey lower cheeks
A weakened skin barrier from years of harsh skincare
Treatment Plan:
Instead of choosing one treatment, we combined:
Profhilo — 2 sessions
To stimulate deep hydration and elasticity and to target crepiness on the lower cheeks and neck.
Fillmed NCTF 135HA — 3 sessions
To brighten, smooth texture, refine pores and support long-term skin quality.
Medical-grade skincare
To repair the barrier and enhance collagen response.
Results:
After 8 weeks, Sarah described her skin as “the best it has looked in years.” We observed:
Brighter complexion
Noticeably smoother texture
Plumper, healthier skin
Reduction in crepiness
Softer neck lines
More even tone
Overall “lit-from-within” glow
She now maintains her results with Profhilo every 6–9 months and skin boosters twice per year.
Profhilo vs other Skin Boosters — Which Should YOU Choose?
Choose Profhilo if you want:
✔ Tighter, firmer skin
✔ Improved cheek and jawline definition
✔ Strong anti-ageing support
✔ Reduction in crepiness
✔ Long-lasting results
✔ Improved skin laxity
Choose Redensity 1 / Fillmed NCTF
if you want:
✔ Hydrated, glowing skin
✔ Smoother texture
✔ Pore refinement
✔ Radiance
✔ Brightening
✔ Early anti-ageing
Choose Polynucleotides
if you want:
✔ Regeneration
✔ Healing
✔ Strengthened skin
✔ Under-eye rejuvenation
✔ Help with rosacea or sensitivity
FAQs — Profhilo & Skin Boosters in Altrincham
1. Which is better — Profhilo or a skin booster?
They serve different purposes. Profhilo lifts and firms; skin boosters hydrate and brighten. Many patients benefit from a combination.
2. How long do results last?
Profhilo: up to 6–9 months
Skin boosters: 4–6 months
Polynucleotides: up to 12 months
Exosomes: cumulative long-term improvements
3. How soon will I see results?
Profhilo: noticeable usually from 4 weeks
Other skin boosters: often immediate glow
Polynucleotides: gradual improvement over 6–8 weeks
4. Is there downtime?
Mild swelling at injection points for 12–48 hours. No major downtime.
5. Can these treatments replace filler?
No — they improve skin quality, not volume or structure. They are ideal for patients wanting natural, non-volumising rejuvenation.
6. Are these treatments safe?
Yes — especially when performed in a doctor-led clinic. Safety, product choice and technique are crucial factors.
7. Which treatment is best for the neck and chest?
Profhilo improves crepiness and laxity; Redensity 1 or NCTF improve hydration and fine lines. Combination treatments offer exceptional results.
8. Will I look “overdone”?
No. These treatments enhance skin quality, not facial shape. Your results remain natural and subtle.
Ready to Transform Your Skin?
If you’re looking for Profhilo treatment in Altrincham, advanced skin boosters in Hale, or regenerative skin rejuvenation tailored to your needs, I’d love to guide you through your options.
📍 Dr Caroline Warden Skin & Aesthetic Clinic — Hale, Altrincham, Cheshire
✨ Female, family-run, doctor-led. Natural results, always.
Book in for a Consultation at your local, doctor-led, sister-run skin & aesthetics sanctuary for natural, bespoke results
Dr Caroline Warden is an experienced NHS GP and aesthetic doctor. She has been a medical doctor for over 18 years. She runs the female-led family business with her sister Louise Devereux (creative director & patient co-ordinator)
Their main Skin and Aesthetic Clinic is located in Hale, Cheshire but they also run a pop-up clinic in Disley, Stockport one evening a week.
You will only ever see and have treatments with Dr Caroline Warden.
Whether you're new to aesthetic treatments or ready to refine your routine, her bespoke skin assessments are the best place to start. Dr Caroline Warden will design a tailored plan based on your skin goals, lifestyle, and timeline.
Book your consultation at the clinic in Hale, Cheshire and experience aesthetic medicine.
You’ll be guided through your medical history, goals, and expectations so you can make an informed choice.
Where our clinics are local to:
Our flagship main Hale clinic is conveniently located for patients travelling from:
Alderley Edge, Altrincham, Bowdon, Bramhall, Hale Barns, Knutsford, Manchester, Mobberley, Sale, Timperley, Urmston, Wilmslow, Handforth, Poynton, Cheadle, Didsbury and Warrington.
Our satellite Disley clinic (Thursday evenings at Scott, Skin & Co) is ideal if you’re based in:
New Mills, High Lane, Marple, Mellor, Whaley Bridge, Strines, Chapel, Hayfield or Stockport.