Last updated: 11 November 2026
In short: At my clinic in Hale, polynucleotides cost £255 per session for the introductory course of three sessions, three to four weeks apart, so £765 for the course, with maintenance sessions at £295 and the option of adding NCTF 135HA to any session for £40. The £75 consultation is redeemable against treatment. The price includes the product, treatment by a doctor using a cannula with local anaesthetic, photographs and a review if you want one. What changes the number is how many areas you treat and whether you add NCTF, not your age.
Local to Hale, Altrincham or Cheshire? I am an NHS GP and aesthetic doctor and run a GP led skin clinic in Hale village, with evening appointments until 7pm on Tuesdays and Wednesdays and until 9pm on Fridays. You can book a consultation or see the full price list.
Polynucleotides have become one of the most searched treatments in aesthetics and one of the least transparently priced. Most clinics quote "from" prices or ask you to book to find out. This page sets out exactly what polynucleotides cost at my clinic, what is included, why the course is three sessions, what the NCTF add on is and whether it is worth £40, and how the cost compares with skin boosters and Sculptra.
In this article:
- Polynucleotide prices in Hale, 2026
- What is included in the price
- Why three sessions, and what maintenance costs
- The NCTF 135HA add on: what it is and whether it is worth it
- Polynucleotide cost compared with skin boosters, Profhilo and Sculptra
- Frequently asked questions
Polynucleotide prices in Hale, 2026
Prices were correct at the date at the top of this page; the price list takes precedence if they differ. The course is paid session by session, not up front, and the introductory rate applies to all three sessions of your first course.
What is included in the price
Why three sessions, and what maintenance costs
Polynucleotides work by signalling your own fibroblasts to repair and rehydrate the skin rather than by filling anything, and that signal needs repeating. The protocol with the best evidence is three sessions three to four weeks apart, then maintenance. One session gives a short lived glow; three sessions give a measurable change in hydration, elasticity and fine lines that lasts.
The maintenance price is deliberately higher than the introductory rate. The introductory course is priced to make the three session protocol affordable, because a single session is poor value and I would rather you did it properly or not at all.
The NCTF 135HA add on: what it is and whether it is worth it
NCTF 135HA is a skin booster containing hyaluronic acid with a cocktail of vitamins, amino acids, minerals and antioxidants. I add it to polynucleotide sessions for £40 because the two do different jobs: the polynucleotides signal repair, and the NCTF supplies hydration and nutrients to the skin that is repairing. It is the only add on I use with polynucleotides, and in my experience it visibly improves the result for most people.
Polynucleotide cost compared with skin boosters, Profhilo and Sculptra
They are not alternatives so much as answers to different questions. If your skin looks tired, thin or crepey, polynucleotides. If it is simply dull and dehydrated, a skin booster. If the face has lost its support, Sculptra. Many people have two of the three over a year. The full comparison is in Profhilo versus polynucleotides versus Sculptra.
Takeaway: Polynucleotides in Hale cost £255 per session for the three session introductory course, £765 in total, with maintenance at £295 and NCTF 135HA added for £40. The £75 consultation comes off your treatment. The price includes the product, treatment by a doctor with a cannula and local anaesthetic, photographs, a skincare check and a review if you want one. Three sessions is the protocol with the evidence; one session is poor value and I would rather you did it properly or chose something else.
Frequently asked questions about polynucleotide cost
How much do polynucleotides cost in Hale and Altrincham?
£255 per session for the introductory course of three, so £765, with maintenance sessions at £295 and the NCTF 135HA add on at £40. The £75 consultation is redeemable against treatment.
Why is the course three sessions?
Because polynucleotides work by repeatedly signalling your skin to repair itself, and the protocol with the best evidence is three sessions three to four weeks apart. One session gives a brief glow; three give a lasting change.
Do I have to pay for the whole course up front?
No. You pay per session at the introductory rate, and the rate applies to all three sessions of your first course.
Why is maintenance more expensive than the course sessions?
The introductory rate is priced to make the proper three session protocol affordable. Maintenance at £295 around every six months is the standard price for a single session.
Is NCTF worth the extra £40?
For most people, yes, particularly for dehydrated or crepey skin and the under eye area. It is the only add on I use with polynucleotides. If budget is tight, the polynucleotides alone are the part that matters most.
How does the cost compare with Profhilo?
Profhilo is a two session course so the total is lower, but it does a different job: hydration and glow rather than repair. For thin, tired or under eye skin, polynucleotides are the better spend.
Next steps
If your skin looks tired, thin or crepey and you want to know what a polynucleotide course would cost for you, with or without NCTF, book a consultation at the clinic in Hale. You will leave with a plan and a price, and no obligation to go ahead.
Learn more about Dr Caroline Warden Clinic
Learn more about other treatments offered
Further reading
- Polynucleotides in Hale and Altrincham (treatment page)
- Profhilo vs Polynucleotides vs Sculptra: Which Do You Need?
- Why I Combine Polynucleotides With Skin Boosters
- Why Collagen Declines and the Treatments That Actually Stimulate It
- How Much Does Sculptra Cost in Hale and Altrincham?
- How Much Does Medical Microneedling Cost in Hale and Altrincham?
- Skin Boosters and Profhilo in Hale and Altrincham
Dr Caroline Warden (GMC 6157708) is an NHS GP with over 19 years of clinical experience, an independent prescriber, and holds a Level 7 postgraduate diploma in cosmetic injectables. She has practised aesthetic medicine since 2017 and is the sole practitioner at Dr Caroline Warden Skin & Aesthetic Clinic, which she runs with her sister Louise at 2 Crown Passages, Hale, Cheshire, WA15 9GN, serving patients from Hale, Altrincham, Bowdon, Hale Barns, Timperley, Sale, Wilmslow, Alderley Edge, Knutsford, Didsbury and across Cheshire and South Manchester. The clinic was named Best Doctor Led Aesthetic Clinic in Cheshire 2026 by GHP. Polynucleotides and NCTF 135HA are medical devices; risks, limitations and alternatives are discussed at consultation, and results vary between individuals. Prices quoted were correct at the date above; the price list takes precedence. The clinic does not diagnose or treat medical conditions. This article provides general information and does not replace an individual consultation.
References
- Dr Caroline Warden Skin & Aesthetic Clinic. Price list. View the price list
- Committee of Advertising Practice. Cosmetic interventions: advertising guidance. Read the guidance
